Professor of Medicine, University of Pennsylvania School of Veterinary Medicine

Chief, Section of Medicine and Ophthalmology, Department of Clinical Studies-New Bolton Center, University of Pennsylvania School of Veterinary Medicine

American College of Veterinary Internal Medicine Specialty of Large Animal Internal Medicine

Clinical Specialties: Large Animal Internal Medicine
Research Areas: Paratuberculosis (Johne's Disease), Pharmacokinetics of antimicrobial drugs, Botulism

Contact Information:
University of Pennsylvania
School of Veterinary Medicine
Dept of Clinical Studies
New Bolton Center
382 West Street Road
 Phone 610-925-6132
 Fax 610-925-6800
 Email rsweeney@vet.upenn.edu

Large Animal Internal Medicine

Paratuberculosis (Johne's Disease)
-Immune Response
-Experimental Infection Models

Pharmacokinetics of antimicrobial drugs

Sweeney RW, Collins MT, Koets AP, McGuirk SM, Roussel AJ ACVIM Consensus Statement: Paratuberculosis (Johne’s Disease) in cattle and other susceptible species Journal of Vet Int Med 26: 1239, 2012.

Fecteau ME, Whitlock RH, Fyock TL, McAdams SC, Boston RC, Sweeney RW Antimicrobial activity of gallium nitrate against Mycobacterium avium subsp. paratuberculosis in neonatal calves J Vet Int Med 25: 1152-1155, 2011.

Sweeney RW, Whitlock RH, Bowersock TL, Cleary DL, Meinert TR, Habecker PL, Pruitt GW Effect of subcutaneous administration of a killed Mycobacterium avium subsp. paratuberculosis vaccine on colonization of tissues following oral exposure to the organism in calves. Am J Vet Res 70: 493-498, 2009.

Sweeney RW., Uzonna J., Whitlock RH., Habecker PL., Chilton P., Scott P. Tissue predilection sites and effect of dose on Mycobacterium avium subs. paratuberculosis organism recovery in a short-term bovine experimental oral infection model Research in Veterinary Science 80: 253-9, 2006.

Uzonna JE., Chilton P., Whitlock RH., Habecker PL., Scott P., Sweeney RW. Efficacy of commercial and field-strain Mycobacterium paratuberculosis vaccinations with recombinant IL-12 in a bovine experimental infection model Vaccine 21: 3101-9, 2003.

Sweeney RW, Whitlock RH, McAdams S Comparison of three DNA preparation methods for real-time PCR confirmation of Mycobacterium avium subsp. paratuberculosis growth in an automated broth culture system Journal Veterinary Diagnostic Investigation 18: 587-590, 2006.

Sweeney RW., Jones DE., Habecker P., Scott P. Interferon-gamma and interleukin 4 gene expression in cows infected with Mycobacterium paratuberculosis American Journal of Veterinary Research 59: 842-7, 1998.

Sweeney RW., Whitlock RH., Rosenberger AE. Mycobacterium paratuberculosis cultured from milk and supramammary lymph nodes of infected asymptomatic cows Journal of Clinical Microbiology 30: 166-71, 1992.

Sweeney RW., Whitlock RH., Buckley CL., Spencer P., Rosenberger AE., Hutchinson LJ. Diagnosis of paratuberculosis in dairy cattle, using enzyme-linked immunosorbent assay for detection of antibodies against Mycobacterium paratuberculosis in milk American Journal of Veterinary Research 55: 905-9, 1994.

Johnson AL, McAdams-Gallagher SC, Sweeney RW Quantitative real-time PCR for detection of neurotoxin genes of Clostridium botulinum types A, B, and C in equine samples Veterinary Journal 199: 157, 2014.

Johnson AL, Burton AJ, Sweeney RW Utility of two immunological tests for antemortem diagnosis of equine protozoal encephalomyelitis (Sarcocystis neurona infection) in naturally occurring cases. J Veterinary Internal Medicine 24: 1184-1189, 2010.

Ross J, Dallap BL, Dolente BA, Sweeney RW Pharmacokinetics and pharmacodynamics of epsilon-aminocaproic acid in horses American Journal of Veterinary Research 68: 1016-1021, 2007.

Sielman ES., Sweeney RW., Whitlock RH., Reams RY. Hypokalemia syndrome in dairy cows: 10 cases (1992-1996) Journal of the American Veterinary Medical Association 210: 240-3, 1997.

A.B. (Chemistry) Dartmouth College, 1978

V.M.D. (Veterinary Medicine) University of Pennsylvania School of Veterinary Medicine, 1982