Deborah C. Silverstein, DVM, DACVECC


    Additional Titles:

    Chief, Section of Emergency & Critical Care, Ryan Veterinary Hospital

    Silverstein DC, Hopper K, eds. “Small Animal Critical Care Medicine,” 3rd Ed, Elsevier, St. Louis, MO, 2023. Also contributed to or wrote the following chapters in this book: de Laforcade A, Silverstein DC. “Classification and Initial Management of Shock States,” Smart L, Silverstein DC. “The Endothelial Surface Layer,” Haskins S, Silverstein DC. “Hypoxemia,” Fischer C, Silverstein DC. “Chest Wall Disease,” de Rosa SM, Silverstein DC. “Respiratory Distress Look-Alikes,” Slensky KS, Silverstein DC. “Mechanical Ventilation-Advanced Concepts,” Liu TYD, Silverstein DC. “Crystalloids and hemoglobin-Based Oxygen Carrying Solutions,” Centola SJ, Silverstein DC. “Colloid Solutions,” Kovak N, Silverstein DC. “Daily Intravenous Fluid Therapy,” Balakrishnan A, Silverstein DC. “Shock Fluids and Fluid Challenge,” Boller EM, Silverstein DC. “Sepsis and Septic Shock,” Hart S, Silverstein DC. “Catecholamines,” Silverstein DC, Hart S. “Vasopressin,” Schaefer J, Silverstein DC. “Fluoroquinolones,” Wolf J, Silverstein DC. “Blood Gas Sampling.”

    Vigano F, Silverstein DC, eds. “Fluid Therapy in Dogs and Cats,” 2nd Ed, Edra-Masson, Milan, Italy, 2023. Also wrote Silverstein DC “The Microcirculation and Fluid Therapy,” and co-authored: Montague B, Silverstein DC “Hemorrhagic Shock.” 

    Drobatz KJ, Hopper K, Rozanski EA, Silverstein DC, ed.  “Textbook of Small Animal Emergency Medicine” 1st Ed, John Wiley and Sons, Inc, Hoboken, NJ, 2019. Also contributed or wrote the following chapters in this book: Pipan M, Silverstein DC. “Diarrhea,” Gonzalez A, Silverstein DC. “Hypoglycemia,” Rabelo R, Silverstein DC. “Emerging Monitoring Techniques,” Hart S, Silverstein DC. “Crystalloid Fluid Therapy.”  

    Vézina-Audette R, Kantyka M, Gianotti G, Silverstein DC. Comparison of mean arterial blood pressure and heart rate changes in response to 3 different isotonic crystalloid boluses in hypotensive anesthetized dogs. Animals 2022;12(14):1781.

      Chalifoux NV, Silverstein DC, Page B, Fudge JM. Assessment of changes in intra-abdominal pressure and perfusion pressure in late-term pregnant queens undergoing elective ovariohysterectomy. JAVMA 2022;83(8):https://doi.org/10.2460/ajvr.22.02.0023

      Hoehne SN, Balakrishnan A, Silverstein DC, Pigott AM, Powell LL, Rozanski E, Tart KM, Boller M, on behalf of the RECOVER CPR Registry Subcommittee. Reassessment Campaign on Veterinary Resuscitation (RECOVER) Initiative small animal CPR Registry Report 2016-2021. J Vet Emerg Crit Care 2022;1-13.

      Dourmashkin LH, Lyons B, Hess RS, Walsh K, Silverstein DC*. Evaluation of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in critically ill dogs. J Vet Emerg Crit Care 2022; 1-7. 

      Murphy KM, Rishniw M, Silverstein DC*. Use of Vasopressors for Treatment of Vasodilatory Hypotension in Dogs and Cats by Diplomates of the American College of Veterinary Emergency and Critical Care, J Vet Emerg Crit Care 2022;32:714-722.

      Burke JE, Hess RS, McEntee EP, Griffin MA, Harmon SM, Silverstein DC*. Hepatic abscessation in dogs: a multicenter study of 56 cases (2010-2019). J Vet Emerg Crit Care 2023;1-11. https://doi.org/10.1111/vec.13340

      Berlin N, Pfaff A, Rozanski EA, Chalifoux NV, Hess RS, Silverstein, DC, Donnino MW. Establishment of a reference interval for thiamine levels in healthy dogs and evaluation of the prevalence of absolute thiamine deficiency in critically ill dogs with and without sepsis using high performance liquid chromatography (HPLC), J Vet Emerg Crit Care 2024;34(1):49-56. doi: 10.1111/vec.13341

      Buriko Y, Clarkin-Breslin R, Chalifoux NV, Silverstein DC*. Comparison of a viscoelastic point of care coagulation monitor with thromboelastography in sick dogs with hemostatic abnormalities, Vet Clin Path 2023;52(2):217-227. 

      Dreese K, Murphy K, Burke J, Silverstein DC*. Seizures in Three Juvenile Dogs After Intravenous Anesthetic Drug Withdrawal During Weaning from Mechanical Ventilation Suspected to be a Sign of Iatrogenic Withdrawal Syndrome, J Vet Emerg Crit Care 2024;34(2):173-178. doi: 10.1111/vec.13366

      Cortellini S, DeClue AE, Goggs R, Giunti M, Hopper K, Menard JM, Rabelo RC, Rozanski EA, Sharp CR, Silverstein DC, Sinnott-Stutzman V, Stanzani G. Defining Sepsis in Small Animals. J Vet Emerg Crit Care2024; 1-13. https://doi.org/10.1111/vec.13359

      Minter LE, Hess RS, Silverstein DC*. Factors associated with tracheal decannulation failure in dogs requiring temporary tracheostomy after upper airway surgery for brachycephalic obstructive airway syndrome, J Vet Emerg Crit Care 025 Mar-Apr;35(2):131-136. doi: 10.1111/vec.13453. Epub 2025 Mar 24. PMID: 40127420.

      Harmon SM, Hess SH, Berlin N, Silverstein DC*. Factors associated with return of spontaneous circulation and survival to hospital discharge in dogs and cats undergoing cardiopulmonary resuscitation using the Reassessment Campaign on Veterinary Resuscitation (RECOVER) database, J Vet Emerg Crit Care 2025 Jun 16:e13473. doi: 10.1111/vec.13473. Epub ahead of print. PMID: 40522688.

      Horridge MV, Lyons BM, Stefanovski D, Silverstein DC*. Development of a novel scoring system to predict mortality in canine patients with infection. J Vet Emerg Crit Care. 2024; 1-5. https://doi.org/10.1111/vec.13405

      Newmans B, Fudge M, Silverstein DC*, Verocai G. Comparison of viscoelastic coagulation parameters, blood loss, and surgical time between asymptomatic heartworm antigen-positive and negative dogs presented for elective gonadectomy, J Small Anim Pract, 2025;1–7. DOI: 10.1111/jsap.13834.

      Stastny T, Silverstein DC, Kerley JB, Hess RS, Mazzeo G, Caldwell DJ, Her J. Prognostic value of end-tidal alveolar dead space fraction in mechanically ventilated dogs. J Vet Emerg Crit Care accepted 4-25.

      Frame J, Fudge J, Hess R, Chalifoux N, Silverstein DC*. Safe use of intraoperative intraperitoneal crystalloid fluid administration in the management of late-term pregnant queens undergoing elective ovariohysterectomy, JAVMA 2025 May 2:1-6. doi: 10.2460/javma.24.12.0769. Epub ahead of print. PMID: 40324476.

          School of Veterinary Medicine, University of California, Davis, CA (1998 to 2001)
          Residency, Small Animal Emergency & Critical Care Medicine

          School of Veterinary Medicine, The University of Georgia, Athens, GA (1997 to 1998)
          Internship, Small Animal Medicine & Surgery

          Clinical Specialties:

          Emergency Services

          Education:

          DVM University of Georgia, 1997
          BS (Biology & Philosophy) Emory University, 1993

          Board Certification:

          Diplomate, American College of Veterinary Emergency and Critical Care

          Contact:

          University of Pennsylvania

          School of Veterinary Medicine

          3800 Spruce Street

          Philadelphia, PA 19104