Our Publications
Combined Hydrogel and Mesenchymal Stem Cell Therapy for Moderate Severity Disc Degeneration in Goats | June 2020 | Tissue Engineering Part A
C. Zhang, S. Gullbrand, T. Schaer, S. Boorman, D. Elliott, W. Chen, G. Dodge, R. Mauck, N. Malhotra, L. Smith
DOI Link: http://dx.doi.org/10.1089/ten.TEA.2020.0103
Inflammatory Cytokine and Catabolic Enzyme Expression in a Goat Model of Intervertebral Disc Degeneration | February 2020 | Journal of Orthopaedic Research
C. Zhang, S. Gullbrand, T. Schaer, Y. Lau, Z. Jiang, G. Dodge, D. Elliott, R. Mauck, N. Malhotra, L. Smith
DOI Link: http://dx.doi.org/10.1002/jor.24639
Fatal Ovarian Hemorrhage Associated With Anticoagulation Therapy in a Yucatan Mini-Pig Following Venous Stent Implantation | January 2020 | Frontiers in Veterinary Science
S. Boorman, H. Douglas, B. Driessen, M. Gillespie, T. Schaer
DOI Link: http://dx.doi.org/10.3389/fvets.2020.00018
Platelet-Rich Plasma Lysate Displays Anti-Biofilm Properties and Restores Antimicrobial Activity Against Synovial Fluid Biofilms In Vitro | January 2020 | Journal of Orthopaedic Research
J. Gilbertie, T. Schaer, A. Schubert, M. Jacob, S. Menegatti, R. Lavoie, L. Schnabel
DOI Link: http://dx.doi.org/10.1002/jor.24584
Accepting Higher Morbidity in Exchange for Sacrificing Fewer Animals in Studies Developing Novel Infection-Control Strategies | December 2019 | Biomaterials
H. Busscher, W. Woudstra, T. van Kooten, P. Jutte, L. Shi, J. Liu, W. Hinrichs, H. Frijlink, R. Shi, J. Liu, J. Parvizi, S. Kates, V. Rotello, T. Schaer, D. Williams, D. Grainger, H. van der Mei
DOI Link: http://dx.doi.org/10.1016/j.biomaterials.2019.119737
Equine or Porcine Synovial Fluid as a Novel Ex Vivo Model for the Study of Bacterial Free-Floating Biofilms that Form in Human Joint Infections | August 2019 | PLoS ONE
J. Gilbertie, L. Schnabel, N. Hickock, M. Jacob, B. Conlon, I. Shapiro, J. Parvizi, T. Schaer
DOI Link: http://dx.doi.org/10.1371/journal.pone.0221012
Clinical Findings, Treatments, and Outcomes in Farm Animals with Vertebral Fractures or Luxations: 22 Cases (2006-2017) | June 2019 | Veterinary and Comparative Orthopaedics and Traumatology
S. Boorman, A. Johnson, T. Schaer, M. Fecteau
DOI Link: http://dx.doi.org/10.1055/s-0039-1692637
The 2018 International Consensus Meeting on Musculoskeletal Infection: Summary from the Biofilm Workgroup and Consensus on Biofilm Related Musculoskeletal Infections | January 2019 | Journal of Orthopaedic Research
K. Saeed, A. McLared, E. Schwarz, V. Antoci, W. Arnold, A. Chen, M. Clauss, J. Esteban, V. Gant, E. Hendershot, N. Hickock, C. Higuera, D. Coraca-Huber, H. Choe, J. Jennings, M. Joshi, W. Li, P. Noble, K. Phillips, P. Pottinger, C. Restrepo, H. Rohde, T. Schaer, H. Shen, M. Smeltzer, P. Stoodley, J. Webb, E. Witso
DOI Link: http://dx.doi.org/10.1055/s-0039-1692637
Recommendations for Design and Conduct of Preclinical In Vivo Studies for Device-Related Infection | January 2019 | Journal of Orthopaedic Research
T. Moriarty, L. Harris, R. Mooney, J. Wenke, M. Riool, S. Zaat, A. Moter, T. Schaer, N. Khanna, R. Kuehl, V. Alt, A. Montali, J. Liu, S. Zeiter, H. Busscher, D. Grainger, R. Richards
DOI Link: http://dx.doi.org/10.1002/jor.24230
Long-Term Mechanical Function and Integration of an Implanted Tissue-Engineered Intervertebral Disc | November 2018 | Science Translational Medicine
S. Gullbrand, B. Ashinsky, E. Bonnevie, D. Kim, J. Engiles, L. Smith, D. Wlliott, T. Schaer, H. Smith, R. Mauck
DOI Link: http://dx.doi.org/10.1126/scitranslmed.aau0670
Gram-negative Multi-drug Resistant Bacteria Influence Survival to Discharge for Horses with Septic Synovial Structures: 206 Cases (2010-2015) | October 2018 | Veterinary Microbiology
J. Gilbertie, L. Schnabel, D. Stefanovski, D. Kelly, M. Jacob, T. Schaer
DOI Link: http://dx.doi.org/10.1016/j.vetmic.2018.10.009
General Assembly, Research Caveats: Proceedings of International Consensus on Orthopedic Infections | October 2018 | The Journal of Arthroplasty
R.Bargon, J. Bruenke, A. Carli, M. Fabritus, R. Goel, K. Goswami, P. Graf, H. Groff, T. Grupp, H. Malchau, M. Mohaddes, C. Novaes de Santana, K. Phillips, H. Rohde, O. Rolfson, A. Rondon, T. Schaer, P. Sculco, K. Svensson
DOI Link: http://dx.doi.org/10.1016/j.arth.2018.09.076
Pooled Platelet-Rich Plasma Lysate Therapy Increases Synoviocyte Proliferation and Hyalauranic Acid Production While Protecting Chondrocytes from Synoviocyte-Derived Inflammatory Mediators | July 2018 | Frontiers in Veterinary Science
J. Gilbertie, J. Long, A. Schubert, A. Berglund, T. Schaer, L. Schnabel
DOI Link: http://dx.doi.org/10.3389/fvets.2018.00150
Evolution of Analgesic and Pharacokinetic Properties of Transdermally Administered Fentanyl in Goats | September 2017 | Journal of Veterinary Emergency and Critical Care
M. Burke, L. Soma, R. Boston, J. Rudy, T. Schaer
DOI Link: http://dx.doi.org/10.1111/vec.12644
Translation of an Injectable Triple-Interpenetrating-Network Hydrogel for Intervertebral Disc Regeneration in a Goat Model | July 2017 | Acta Biomaterialia
S. Gullbrand, T. Schaer, P. Agarwal, J. Bendigo, G. Dodge, W. Chen, D. Elliott, R. Mauck, N. Malhotra, L. Smith
DOI Link: http://dx.doi.org/10.1016/j.actbio.2017.07.025
A Large Animal Model that Recapitulates the Spectrum of Human Intervertebral Disc Degeneration | August 2016 | Osteoarthritis and Cartilage
S. Gullbrand, N. Malhotra, T. Schaer, Z. Zawacki, J. Martin, J. Bendigo, A. Milby, G. Dodge, E. Vresilovic, D. Elliott, R. Mauck, L. Smith
DOI Link: http://dx.doi.org/10.1016/j.joca.2016.08.006
Cyclodextrins Affect Positive Arterial Wall Remodeling in Atherosclerotic Injury Model | April 2016 | Journal of American College of Cardiology
M. Saybolt, S. Anwaruddin, D. Hamamdzic, T. Schaer, R. Wilensky
DOI Link: http://dx.doi.org/10.1016/S0735-1097(16)30165-6
Micron-thin Bactericidal Sol-Gel Coated Intramedullary Nails for the Prevention and Treatment of Infetion | January 2016 | Frontiers in Bioengineering and Biotechnology
H. Qu, C. Knabe, Z. Zawacki, T. Schaer, P. Ducheyne
DOI Link: http://dx.doi.org/10.3389/conf.FBIOE.2016.01.02341
Effects of Mesenchymal Stem Cell and Growth Factor Delivery on Cartilage Repair in a Mini-Pig Model | December 2016 | Cartilage
M. Fisher, N. Belkin, A. Milby, E. Henning, N. Soegaard, M. Kim, C. Pfeiffer, V. Saxena, G. Dodge, J. Burdick, T. Schaer, D. Steinberg, R. Mauck
DOI Link: http://dx.doi.org/10.1177/1947603515623030
Risk Factors Associated with Survival to Hospital Discharge of 54 Horses with Fractures of the Radius | October 2015 | Veterinary Surgery
S. Stewart, D. Richardson, R. Boston, T. Schaer
DOI Link: http://dx.doi.org/10.1111/vsu.12412
Repair of Dense Connective Tissues via Biomaterial-Mediated Matrix Reprogramming of the Wound Interface | November 2014 | Biomaterials
F. Qu, M. Pintauro, J. Haughan, E. Henning, J. Esterhai, T. Schaer, R. Mauck, M. Fisher
DOI Link: http://dx.doi.org/10.1016/j.biomaterials.2014.10.067
Injectable Radiopaque and Bioactive Polycaprolactone-ceramic Composites for Orthopedic Augmentation | November 2014 | Journal of Biomedical Materials Research Part B Applied Biomaterials
Y. Jung No, S. Roohani-Esfahani, Z. Lu, T. Schaer, H. Zreiqat
DOI Link: http://dx.doi.org/10.1002/jbm.b.33336
Cartilage Repair and Subchondral Bone Remodeling in Response to Focal Lesions in a Mini-Pig Model: Implications for Tissue Engineering | October 2014 | Tissue Engineering Part A
M. Fisher, N. Belkin, A. Milby, E. Henning, M. Bostrom, M. Kim, C. Pfeifer, G. Meloni, G. Dodge, J. Burdick, T. Schaer, D. Steinberg, R. Mauck
DOI Link: http://dx.doi.org/10.1089/ten.TEA.2014.0384
Arthroscopy of the Normal Cadaveric Ovine Femoro-Tibial Joint: A Systematic Approach to the Cranial and Caudal Compartments | September 2014 | Veterinary and Comparative Orthopedics and Traumatology
R. Modesto, K. Mansmann, T. Schaer
DOI Link: http://dx.doi.org/10.3415/VCOT-14-03-0039
Bactericidal Micron-Thin Sol-Gel Films Prevent Pin Tract and Periprosthetic Infection | August 2014 | Military Medicine
H. Qu, C. Knabe, M. Burke, S. Radin, J. Garino, T. Schaer, P. Ducheyne
DOI Link: http://dx.doi.org/10.7205/MILMED-D-13-00494
Prosthesis Selection | December 2013 | The Journal of Arthroplasty
C. Diaz-Ledezma, J. Parvizi, Y. Zhou, V. Antoci, P. Ducheyne, A. Frieberg, G. Rangel, S. Han, N. Hickock, C. Higuera, C. Ketonis, F. Korkusuz, J. Kruczynski, F. Macule, J. Markuszewski, O. Marin-Pena, D. Nathwani, P. Noble, K. Ong, N. Ono, M. Parvizi, Z. Post, S. Rivero-Boschert, T. Schaer, I. Shapiro
DOI Link: http://dx.doi.org/10.1016/j.arth.2013.09.039
Vancomycin-Modified Implant Surface Inhibits Biofilm Formation and Supports Bone-Healing in an Infected Osteotomy Model in Sheep: A Proof-of-Concept Study | August 2012 | The Journal of Bone and Joint Surgery
S. Stewart, S. Barr, J. Engiles, N. Hickock, I. Shapiro, D. Richarson, J. Parvizi, T. Schaer
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401139/
Molecular Engineering of an Orthopedic Implant: From Bench to Bedside | May 2012 | European Cells & Materials
I. Shapiro, N. Hickock, J. Parvizi, S. Stewart, T. Schaer
DOI Link: http://dx.doi.org/10.22203/eCM.v023a28
Comparison of Animal Discs Used in Disc Research to Human Lumbar Disc | February 2012 | Spine
B. Showalter, J. Beckstein, J. Martin, E. beattie, A. Orias, T. Schaer, E. Vresilovic, D. Elliott
DOI Link: http://dx.doi.org/10.1097/BRS.0b013e31824d911c
Hydrophobic Polycationic Coatings that Inhibit Biofilms and Support Bone Healing During Infection | November 2011 | Biomaterials
T. Schaer, S. Stewart, B. Hsu, A. Klibanov
DOI Link: http://dx.doi.org/10.1016/j.biomaterials.2011.10.038
Influence of a Resilient, Hard-Carbon Thin Film on Drilling Efficiency and Thermogenesis | October 2011 | Veterinary Surgery
J. Gasiorowski, D. Richardson, R. Boston, T. Schaer
DOI Link: http://dx.doi.org/10.1111/j.1532-950X.2011.00894.x
Biomaterials for Replacement and Repair of Meniscus and Annulus Fibrosis | October 2011 | Comprehensive Biomaterials
D. Elliott, R. Mauck, R. Shah, T. Schaer, S. Maher
DOI Link: http://dx.doi.org/10.1016/B978-0-08-055294-1.00173-2
Intravenous Technetium-99m Labeleld PEG-Liposomes in Horses: A Safety and Biodistribution Study | June 2011 | Equine Veterinary Journal
C. Underwood, A. Van Eps, M. Ross, P. Laverman, L. Van Bloois, G. Storm, T. Schaer
DOI Link: http://dx.doi.org/10.1111/j.2042-3306.2011.00403.x
Disc Torsion Mechanics: Comparison of Animal Models to Human | June 2011 | ASME Summer Bioengineering Conference
B. Showalter, J. Beckstein, J. Martin, E. Beattie, A. Esponoza Orias, T. Schaer, E. Vresilovic, D. Elliott
DOI Link: http://dx.doi.org/10.1115/SBC2011-53607
Evaluation of Equine Peripheral Blood Apheresis Product, Bone Marrow, and Adipose Tissue as Sources of Mesenchymal Stem Cells and Their Different Potential | January 2011 | American Journal of Veterinary Research
B. Ahern, T. Schaer, S. Tekhorn, K. Jackson, N. Mason, K. Hankenson
DOI Link: http://dx.doi.org/10.2460/ajvr.72.1.127
Perioperative Ruminal pH Changes in Domestic Sheep (Ovis aries) Housed in a Biomedical Research Setting | January 2011 | Journal of the American Association for Laboratory Animal Science
B. Jasmin, R. Boston, R. Modesto, T. Schaer
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035399/
Pharmacokinetics of Fentanyl Administered Transdermally and Intravenously in Sheep | October 2010 | American Journal of Veterinary Research
B. Ahern, L. Soma, J. Rudy, C. Uboh, T. Schaer
DOI Link: http://dx.doi.org/10.2460/ajvr.71.10.1127
Towards an Understanding of the Role of Notochordal Cells in the Adult Intervertebral Disc: From Discord to Accord | August 2010 | Developmental Dynamics
M. Risbud, T. Schaer, I. Shapiro
DOI Link: http://dx.doi.org/10.1002/dvdy.22350
Evaluation of a Fiber Reinforced Drillable Bone Cement for Screw Augmentation in a Sheep Model-Mechanical Testing | June 2010 | Clinical and Translational Science
B. Ahern, R. Harten, E. Gruskin, T. Schaer
DOI Link: http://dx.doi.org/10.1111/j.1752-8062.2010.00201.x
Orthopedic Infections in Equine Long Bone Fractures and Arthrodeses Treated by Internal Fixation: 192 Cases (1990-2006) | April 2010 | Veterinary Surgery
B. Ahern, D. Richardson, R. Boston, T. Schaer
DOI Link: http://dx.doi.org/10.1111/j.1532-950X.2010.00705.x
Pneumopericardium in a Horse Secondary to Sternal Bone Marrow Aspiration | January 2010 | Equine Veterinary Education
M. Durando, L. Zarucco, T. Schaer, M. Ross, V. Reef
DOI Link: http://dx.doi.org/10.1111/j.2042-3292.2006.tb00419.x
Disseminated Blastomycosis in a Miniature Horse | January 2010 | Equine Veterinary Education
B. Dolente, P. Habecker, K. Chope, K. MacGillivray, T. Schaer
DOI Link: http://dx.doi.org/10.1111/j.2042-3292.2003.tb00232.x
Evaluation of a Novel Surgical Technique in an In Vivo Ovine Model to Access the Posterior Horn of the Medial Meniscus | September 2009 | Osteoarthritis and Cartilage
R. Modesto, R. Mauck, B. Baker, C. Underwood, T. Schaer
DOI Link: http://dx.doi.org/10.1016/S1063-4584(09)60103-5
Comparison of the Analgesic Properties of Transdermally Administered Fentanyl and Intramuscularly Administered Buprenorphine During and Following Experimental Orthopedic Surgery in Sheep | April 2009 | American Journal of Veterinary Research
B. Ahern, L. Soma, R. Boston, T. Schaer
DOI Link: http://dx.doi.org/10.2460/ajvr.70.3.418
Meniscus Tissue Engineering on the Nanoscale-From Basic Principles to Application | February 2009 | Journal of Knee Surgery
B. Baker, A. Gee, N. Sheth, G. Huffman, B. Sennett, T. Schaer, R. Mauck
DOI link: http://dx.doi.org/10.1055/s-0030-1247727
Preclincal Animal Models in Single Site Cartilage Defect Testing: A Systematic Review | December 2008 | Osteoarthritis and Cartilage
B. Ahern, J. Parvizi, R. Boston, T. Schaer
DOI Link: http://dx.doi.org/10.1016/j.joca.2008.11.008
51 Preclinical Animal Models in Single Site Cartilage Defect Testing: A Systematic Review | September 2008 | Osteoarthritis and Cartilage
B. Ahern, J. Parvizi, R. Boston, T. Schaer
DOI Link: http://dx.doi.org/10.1016/S1063-4584(08)60098-9
Percutaneous Endovascular Retrieval of an Intravascular Foreign Body in Five Dogs, a Goat, and a Horse | July 2008 | Journal of the American Veterinary Medical Association
W. Culp, C. Weisse, A. Berent, L. Getman, T. Schaer, J. Solomon
DOI Link: http://dx.doi.org/10.2460/javma.232.12.1850
Clostridium Perfringens Urachitis and Uroperitoneum in 2 Neonatal Foals | June 2008 | Journal of Veterinary Internal Medicine
S. Hyman, P. Wilkins, J. Palmer, T. Schaer, F. Del Piero
DOI Link: http://dx.doi.org/10.1111/j.1939-1676.2002.tb01270.x
Comparison of Animal Discs Used in Disc Research to Human Lumbar Disc | April 2008 | Spine
J. Beckstein, S. Sen, T. Schaer, E. Vresilovic, D. Elliott
DOI Link: http://dx.doi.org/10.1097/BRS.0b013e318166e001
Evaluation of a Novel Model of Equine Superficial Digital Flexor Tendonitis in Regenerative Tendon Research | January 2008 | Veterinary Surgery
S. Zedler, T. Schaer, A. Ebling, D.W. Richardson
Link:https://www.researchgate.net/publication/311964319_Evaluation_of_a_novel_model_of_equine_superficial_digital_flexor_tendonitis_in_regenerative_tendon_research
Nucleus Pulposus Cells Express HIF-1α Under Normoxic Culture Conditions: A Metabolic Adaptation to the Intervertebral Disc Microenvironment | May 2006 | Journal of Cellular Biochemistry
M. Risbud, A. Guttapalli, D. Stokes, D. Hawkins, K. Danielson, T. Schaer, T. Albert, I. Shapiro
DOI Link: http://dx.doi.org/10.1002/jcb.20765
Rupture of the Gastrocnemius Muscle in Six Foals | January 2006 | Journal of the American Veterinary Medical Association
S. Jesty, J. Palmer, E. Parente, T. Schaer, P. Wilkins
DOI Link: http://dx.doi.org/10.2460/javma.2005.227.1965
Conservative Management of 17 Horses with Nonarticular Fractures of the Tibial Tuberosity | April 2003 | Equine Veterinary Journal
C. Arnold, T. Schaer, D. Baird, B. Martin
DOI Link: http://dx.doi.org/10.2746/042516403776114261
Clostridium Perfringens Urachitis and Uroperitoneum in 2 Neonatal Foals | July 2002 | Journal of Veterinary Internal Medicine
S. Hyman, P. Wilkins, J. Palmer, T. Schaer, F. Del Piero
DOI Link: http://dx.doi.org/10.1892/0891-6640(2002)162.0.CO;2
Proximal Interphalangeal Arthrodesis in 22 Horses | August 2001 | Equine Veterinary Journal
T. Schaer, L. Bramlage, R. Embertson, S. Hance
DOI Link: http://dx.doi.org/10.2746/042516401776249552
