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Science & Research News


Ebola

Harnessing an innate protection against Ebola

In their evolutionary battle for survival, viruses have developed strategies to spark and perpetuate infection. Once inside a host cell, the Ebola virus, for example, hijacks molecular pathways to replicate itself and eventually make its way back out of the cell into the bloodstream, where it can spread further.

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Dr. William Beltran named One of Eight Penn professors elected 2022 AAAS Fellows

Eight faculty from four University of Pennsylvania schools have been elected 2022 American Association for the Advancement of Science (AAAS) Fellows. They are among more than 500 researchers honored for their “scientifically and socially distinguished achievements.” 

How sex differences may influence lung injury

How sex differences may influence lung injury

Comparing lung cells from male and female mice, Penn Vet scientists found gene expression differences that may explain why older males are at a higher risk than females for worse outcomes from COVID-19 and similar diseases.

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A target for improving recovery from lung injury

After a bout of severe respiratory disease, some patients never fully recover. New research from Penn Vet identifies a factor responsible for inappropriate tissue regrowth after infection, pointing to a possible therapeutic target.

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People and places at Penn: Research

From Charles Addams Fine Arts Hall to the Schuylkill River, four researchers share their science and their spaces, including Penn Vet's Roderick Gagne, assistant professor of wildlife disease ecology.

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Penn Vet’s Dr. Nicola “Nicky” Mason Appears on 60 Minutes

The interview highlighted Dr. Mason’s role in leading clinical trials that evaluated a novel Listeria-based vaccine to treat pet dogs with osteosarcoma, a common canine bone cancer.

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Recreating the adrenal gland in a petri dish

A Penn Vet–led team coaxed stem cells to take on the characteristics and functions of a human adrenal gland, progress that could lead to new therapies for adrenal insufficiencies and a deeper understanding of the genetics of such disorders.

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A FLASH of radiation may lead to new cancer care for people and pets alike

Led by the Perelman School of Medicine’s Keith Cengel and the School of Veterinary Medicine’s Brian Flesner, a new study is evaluating the safety and efficacy of treating oral cancer in dogs with a palliative radiation in just two clinic visits.

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Dr. William Beltran Named Corinne R. and Henry Bower Professor of Ophthalmology at the University of Pennsylvania’s School of Veterinary Medicine

Andrew M. Hoffman, DVM, DVSc, DACVIM, Gilbert S. Kahn Dean of the School of Veterinary Medicine at the University of Pennsylvania (Penn Vet) has named William Beltran, DVM, MSc, PhD, DECVO, an internationally recognized veterinary ophthalmologist, the Corinne R. and Henry Bower Professor of Ophthalmology.

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NIH-funded canine immunotherapy data center charts a path toward transformative therapies

With support recently for five more years, Nicola Mason of the School of Veterinary Medicine and Qi Long of the Perelman School of Medicine hope their work leads to new insights in cancer care for people as well as pets.

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University of Pennsylvania School of Veterinary Medicine Launches New Center for Stewardship Agriculture and Food Security

Drawing on multi-disciplinary expertise, the Center seeks to improve animal agriculture while mitigating climate and ecological impacts.

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Making ‘true’ equine IVF a reproducible success

A new method developed by Katrin Hinrichs and colleagues in the School of Veterinary Medicine resulted in the birth of three healthy foals. The technique opens the door to new insights in the basic biology of horse reproduction.

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T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response

Penn Vet have uncovered a detailed mechanism by which tumors can skirt both the immune system and cancer therapies that leverage its power.

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Cooler temps and northern climes associated with increased diabetes diagnoses in dogs

Mirroring a finding in humans, diabetes diagnoses in dogs were more common in colder areas of the U.S. and during winter, according to a new study led by Penn Vet researchers.

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Igor Brodsky, PhD, Named Inaugural Robert R. Marshak Professor at the University of Pennsylvania’s School of Veterinary Medicine

Dean Andrew M. Hoffman has named Dr. Igor Brodsky, an internationally recognized microbiologist, the inaugural Robert R. Marshak Professor.

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Progress toward a stem cell–based therapy for blindness

A multi-institutional effort led by researchers at Penn Vet is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.

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The University of Pennsylvania’s School of Veterinary Medicine Announces Infectious and Zoonotic Disease Pilot Awards

Awards represent the Institute for Infectious and Zoonotic Diseases’ long-term vision of supporting research that advances understanding of infectious diseases.

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The Institute for Infectious and Zoonotic Diseases at the University of Pennsylvania’s School of Veterinary Medicine to Fund Postdoctoral Fellowship

The postdoctoral fellowship will support scientists conducting research related to the biology of infectious disease.

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University of Pennsylvania’s School of Veterinary Medicine Awarded Nearly $1 Million to Increase Efficiency of Dairy Herds and Reduce Methane Emissions

Principal investigator Dipti Pitta, MVSc, PhD, receives grant from the USDA’s National Institute of Food and Agriculture to build upon pioneering research on rumen microbiota and nutrient utilization.

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A newly identified stem cell regulator enables lifelong sperm production

Research led by Dr. Jeremy Wang has discovered that the enzyme DOT1L, a stem cell renewal factor, is essential for mice to produce sperm throughout their adult lives.