Research Area
New Study Identifies Promising Inhibitor Combination for Hard-to-Treat Leukemia Subtypes
Faculty In This Story Assistant Professor of Biomedical Sciences M. Andrés Blanco, PhD, from the University of Pennsylvania’s School of Veterinary Medicine (Penn Vet) and investigators from the Universities of…
Identifying a proliferating repairman for tissue in damaged lungs (link is external)
Penn Vet and Penn Medicine researchers found that endothelial cells lining the veins in lungs contribute to repair of blood vessels after lung injury.
Uncovering a way for pro-B cells to change trajectory (link is external)
Researchers from the School of Veterinary Medicine and Perelman School of Medicine have found that YY1 knockout pro-B cells can generate T lineage cells helping B cells produce antibodies.
University of Pennsylvania School of Veterinary Medicine Biomedical Sciences Researcher Named 2024 Packard Fellow
Andrew Modzelewski, PhD, Receives $875,000 in Support from David and Lucile Packard Foundation for Work on Genome Regulation.
An integral T cell pathway helps regulate female gene expression (link is external)
Penn Vet researchers have revealed a connection between NF-κB signaling pathways and X chromosome inactivation, which has implications for understanding sex-based immune responses during infection.
Penn Vet and Penn Medicine Researchers Receive Nearly $6 Million in Renewed NIH Funding to Study Epigenetics of Reproduction in Animals and Humans
A multidisciplinary group of researchers from the University of Pennsylvania’s School of Veterinary Medicine (Penn Vet) and the University’s Perelman School of Medicine (Perelman) have received $5.95 million in renewed…
A modified peptide shows promise for fighting tumors (link is external)
Researchers in Penn Vet led a collaborative study that demonstrates how a modified peptide normalizes tumor vasculature and enhances various cancer treatments.
Kotaro Sasaki and his team unveil the genetics of testicular cancer (link is external)
Researchers develop the first in vitro seminoma model, shedding light on chromosomal anomalies and signaling pathways.
Removing the barrier surrounding solid tumors clears path for T cells (link is external)
Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor…
Genetic switch turns tumor suppressor into oncogene in colorectal cancer (link is external)
Researchers from the School of Veterinary Medicine have shown that an enzyme that suppresses early-stage colorectal cancer switches to become an oncogene as the cancer progresses.