Penn Today

    Two men in lab coats look at petri dish

    Stress tested, testing stress: Novel organoid models how the adrenal gland develops (link is external)

    Researchers led by Penn Vet’s Kotaro Sasaki and Michinori Mayama have developed an organoid system that faithfully mimics how the human adrenal gland develops and forms complex tissue structures, providing…

    FAP-CAR T cells deplete tumor associated FAP+ fibroblasts and enhance T-cell infiltration FAP-CAR-tLNPs treated group when compared to control (PBS) group.

    Targeting tumor supporting cells: Advancing CAR T success in pancreatic cancer (link is external)

    Research led by Penn Vet’s Ellen Puré has used lipid nanoparticles to generate CAR T cells directed at a type of tumor support cells—cancer-associated fibroblasts—melting away the protective barrier around…

    Amanda Watkins

    Advancing veterinary medicine through interdisciplinary research
 (link is external)

    For many, veterinary school is the gateway to a clearly defined career — diagnosing and treating animals in a clinical setting. But for Amanda Watkins, that journey took an unexpected…

    A black lab being trained to sniff for specific items.

    Sniffing out cancer: Trained dogs can detect hemangiosarcoma by scent (link is external)

    Penn Vet’s Cynthia M. Otto and Clara Wilson and colleagues show that trained dogs can identify the odor of hemangiosarcoma, a devastating canine cancer, offering the hope of a better…

    Histopathology tissue sections of the normal colon

    Identifying genes that keep cancer from spreading (link is external)

    Using a novel approach, Penn Vet’s Chris Lengner and M. Andrés Blanco and colleagues have identified two genes that suppress colorectal cancer metastasis.

    A group of canadian geese

    Wild birds are driving the current U.S. bird flu outbreak (link is external)

    Since late 2021, a panzootic, or “a pandemic in animals,” of highly pathogenic bird flu variant H5N1 has devastated wild birds, agriculture, and mammals.

    three people posing with a dog in a veterinary office

    Dogs with cancer are helping save lives—both canine and human (link is external)

    The Comparative Immunotherapy Program led by Penn Vet’s Nicola Mason is redefining how therapies are developed and tested—uniting human and veterinary medicine to move promising immunotherapies forward.

    A cow sitting in a field

    Applying design to agriculture for a new approach to agroforestry (link is external)

    Agriculture is a key sector of the U.S. economy, generating over $1 trillion annually and supporting millions of jobs. It’s also one of the country’s largest land uses; according to…

    a person in blue gloves holding a syringe above some eggs

    Keeping food safe and animals healthy (link is external)

    A strain of the H5N1 virus—best known for causing avian influenza—was detected in U.S. dairy cattle for the first time in March 2024. It has since spread to more than…

    Black and white cows on a farm eating

    Food waste: Recycling, not discarding, offers huge environmental benefits (link is external)

    Researchers at Penn Vet examine how common food waste recycling methods, including composting, could have a big impact on greenhouse gas emissions and the use of natural resources.

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