Clinical Trials

    Randomized Controlled Trial of One Versus Two Lung Ventilation in Elective Open Lung Lobectomy

    One-lung ventilation (OLV) is an anesthesia technique by which only the lung not undergoing surgery receives oxygen and gas. When the lung that is undergoing surgery is no longer inflated…

    Evaluation of Proton FLASH-RT in Naturally Occurring Canine Extremity Sarcoma

    Proton FLASH radiation therapy (FLASH-RT) is an investigational approach using ultra-high dose “RATE” radiation therapy. This means that the dose(s) of radiation is delivered in a fraction of a second.…

    Cell Therapy for Metastatic Osteosarcoma

    In this study we will investigate the therapeutic potential of a type of white blood cell known as invariant natural killer T (iNKT) cells that are made from the blood…

    PSMA Ligand Based Theranostic to Treat Canine Prostatic Cancer

    The purpose of this study is to assess a new targeted investigational agent called PSMA-MMAE-Pc413 combined with a laser in local and metastatic disease in dogs diagnosed with prostate cancer.

    Social determinants of dog behavior

    The environments where people are born, live, learn, work, and age can have drastic impacts on their health. As humans and pets share physical and social environments, these same environmental…

    Feasibility and perioperative outcomes regarding ultra-low dose indocyanine green for indirect cholangiography during laparoscopic cholecystectomy in dogs

    Laparoscopic cholecystectomy is a minimally invasive surgery to remove the gallbladder. This is commonly performed in people with gallbladder disease such as inflammation, infection, or mucocele formation.

    Equine Lameness Study Osteoarthritis

    In this double-masked, sham-controlled, randomized study, VH-750 will be administered intra-articularly to horses with mild to moderate limb lameness caused by joint OA (fetlock, carpal, or coffin joints).

    Palliative-intent radiation therapy and frunevetmab (Solensia) for feline bone-invasive oral squamous cell carcinoma: A pilot study.

    This study will be the first to assess whether Solensia, in combination with meloxicam and palliative-intent radiation therapy, provides superior pain relief compared to meloxicam and radiation therapy alone. Meloxicam,…

    Embolization or chemoembolization in dogs with hepatocellular carcinoma and utility of contrast-enhanced ultrasound versus CT angiogram in post-embolization assessment

    This trial will compare outcomes in dogs treated with embolization vs. chemoembolization and will also evaluate the accuracy of contrast enhanced ultrasound verses CT angiogram for post-embolization assessment.

    Evaluation of VetResQ® Hemoperfusion Cartridge for Treatment of Non-Steroidal Anti-Inflammatory Drug (NSAID) Toxicity in Dogs and Cats

    The aim of this study is to document how much NSAID is removed from the blood during treatment with VetResQ® hemoperfusion cartridge.

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