30th Anniversary Research Retreat

Robert R. Marshak Lecture

Using the immune system as our new drug paradigm:
From T cell exhaustion to Immune Health

E. John Wherry, Ph.D.
Richard and Barbara Schiffrin President’s Distinguished Professor
Director, Institute for Immunology
Chair, Department of Systems Pharmacology & Translational Therapeutics
Perelman School of Medicine

Dr. E. John Wherry is a professor of immunology and the director of the Institute for Immunology at the Perelman School of Medicine. Dr. Wherry’s research focuses on T cell exhaustion in chronic infections and cancer and on the mechanisms by which immunoregulatory “checkpoint” pathways, such as PD-1, control T cell exhaustion. His work has advanced the understanding of how gene expression changes affect this exhaustion, which has led to strategies to improve the effectiveness of T cell targeting immunotherapies.

The Robert R. Marshak Lectureship was established in 1993, in honor of Dean Emeritus Robert Marshak, the ninth dean of the School of Veterinary Medicine.

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