News Articles

Scientists at the University of Pennsylvania’s School of Veterinary Medicine Shed New Light on the Evolution of Adaptive Immunity in Cold-Blooded Vertebrates
[December 1, 2023; Philadelphia, PA] – Upon infection or immunization, all jawed vertebrate species generate proteins called antibodies that bind and neutralize pathogens. Strong and long-lasting antibody responses in warm-blooded…

Uncovering the role of skin microbiome and immune response in cutaneous leishmaniasis (link is external)
Two new studies led by Phillip Scott of the School of Veterinary Medicine and Elizabeth Grice of the Perelman School of Medicine demonstrate how bacteria found in leishmaniasis skin lesions…

Study shows promise for iNKT cell platform to treat cancer (link is external)
Researchers from the School of Veterinary Medicine and Perelman School of Medicine have shown that invariant natural killer T cells from a healthy donor can persist in MHC-mismatched canines, demonstrating…

Removing the barrier surrounding solid tumors clears path for T cells (link is external)
Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor…

Genetic switch turns tumor suppressor into oncogene in colorectal cancer (link is external)
Researchers from the School of Veterinary Medicine have shown that an enzyme that suppresses early-stage colorectal cancer switches to become an oncogene as the cancer progresses.

Could we breed cows that emit less methane? (link is external)
In a new study, researchers from the School of Veterinary Medicine identified attributes of low-methane-emitting dairy cows that could be used as targets for selective breeding.

Two Early-Career Investigators from the University of Pennsylvania’s School of Veterinary Medicine Recognized for Advancing Biomedical Research
June 20, 2023; PHILADELPHIA, PA – Two early-career scientists from the Department of Biomedical Sciences at the University of Pennsylvania’s School of Veterinary Medicine (Penn Vet) have been honored with…

Harnessing an innate protection against Ebola (link is external)
In their evolutionary battle for survival, viruses have developed strategies to spark and perpetuate infection. Once inside a host cell, the Ebola virus, for example, hijacks molecular pathways to replicate…

How sex differences may influence lung injury (link is external)
Comparing lung cells from male and female mice, Penn Vet scientists found gene expression differences that may explain why older males are at a higher risk than females for worse…

Penn Vet’s Dr. Nicola “Nicky” Mason Appears on 60 Minutes
The interview highlighted Dr. Mason’s role in leading clinical trials that evaluated a novel Listeria-based vaccine to treat pet dogs with osteosarcoma, a common canine bone cancer.
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