Elizabeth M. Lennon, DVM, PhD, DSAIM
Dr. Elizabeth Lennon is a board certified internal medicine specialist and the Pamela L. Cole Assistant Professor of Small Animal Internal Medicine at the University of Pennsylvania. Dr. Lennon’s laboratory studies intestinal mucosal immunology. Dr. Lennon earned her veterinary degree from North Carolina State University (NCSU), and then completed a rotating internship at the University of Pennsylvania. She returned to NCSU where she completed a small animal internal medicine residency and achieved ACVIM board certification. Following her residency, she completed a PhD in intestinal physiology and mucosal immunology from NCSU. Her research is focused on understanding inflammatory and immunoregulatory mechanisms in the intestine and their application to inflammatory bowel disease and SARS-CoV-2 intestinal infection, to benefit humans, dogs, and cats.
Pohl Calvin S, Lennon Elizabeth M, Li Yihang, DeWilde Morgan P, Moeser Adam J S. Typhimurium challenge in juvenile pigs modulates the expression and localization of enteric cholinergic proteins and correlates with mucosal injury and inflammation. Autonomic neuroscience : basic & clinical 213: 51-59, 2018.
Lennon, E. M., Borst, L. B., Edwards, L. L., Moeser, A. J. Mast cells exert anti-inflammatory effects in an IL10(-/-) model of spontaneous colitis Mediators Inflamm 2018: 7817360, 2018.
Pohl, C. S., Lennon, E. M., Li, Y., DeWilde, M. P., Moeser, A. J. S. Typhimurium challenge in juvenile pigs modulates the expression and localization of enteric cholinergic proteins and correlates with mucosal injury and inflammation Auton Neurosci 213: 51-59, 2018.
Lennon, E. M., Hummel, J. B., Vaden, S. L. Urine sodium concentrations are predictive of hypoadrenocorticism in hyponatraemic dogs: a retrospective pilot study J Small Anim Pract 59: 228-231, 2018.
Cooper, R. L., Drobatz, K. J., Lennon, E. M., Hess, R. S. Retrospective evaluation of risk factors and outcome predictors in cats with diabetic ketoacidosis (1997-2007): 93 cases J Vet Emerg Crit Care (San Antonio) 25: 263-72, 2015.
Lennon, E. M., Hanel, R. M., Walker, J. M., Vaden, S. L. Hypercoagulability in dogs with protein-losing nephropathy as assessed by thromboelastography J Vet Intern Med 27: 462-8, 2013.
Lennon, E. M., Maharshak, N., Elloumi, H., Borst, L., Plevy, S. E., Moeser, A. J. Early life stress triggers persistent colonic barrier dysfunction and exacerbates colitis in adult IL-10-/- mice Inflamm Bowel Dis 19: 712-9, 2013.
Lennon, E. M., Hanel, R. M., Vaden, S. L. Thromboelastography in non-azotemic and azotemic dogs with protein-losing nephropathy J Vet Intern Med 25: 718, 2011.
Lennon, E. M., Hummel, J. B., Vaden, S. L. Urine sodium concentrations in hyponatremic dogs with hypoadrenocorticism J Vet Intern Med 24: 686, 2010.
Lennon, E. M., Boyle, T. E., Hutchins, R. G., Friedenthal, A., Correa, M. T., Bissett, S. A., Moses, L. S., Papich, M. G., Birkenheuer, A. J. Use of basal serum or plasma cortisol concentrations to rule out a diagnosis of hypoadrenocorticism in dogs: 123 cases (2000-2005) J Am Vet Med Assoc 231: 413-6, 2007.
The overriding goal of my research is to elucidate the mechanism of the protective role of the mast cell in IBD. The long-term goal of my laboratory is to discover new functions of mast cells that could be used for design of new medications. Mast cells are ideal therapeutic targets due to their host of unique mediators that are not present in other cell types, but we are just beginning to understand some of their important functions, such as their anti-inflammatory activities.
Dr. Lennon is board certified in small animal internal medicine by the American College of Veterinary Internal Medicine. She has a special interest in gastroenterology with an emphasis on inflammatory bowel disease, chronic enteropathy, and intestinal lymphangiectasia.
Clinical Specialties:
gastroenterology, nephrology, urology, IBD in dogs
Research:
Hospital & Services:
Education:
PhD (Comparative Biomedical Sciences) North Carolina State University, 2015
DVM (Veterinary Medicine) North Carolina State University, 2007BS (Animal Sciences) University of New Hampshire, 2002
Board Certification:
Diplomate, American College of Veterinary Internal Medicine (SAIM)
Contact:
University of Pennsylvania
School of Veterinary Medicine
3800 Spruce Street
Philadelphia, PA 19104