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    Katrin Hinrichs, DVM, PhD, DACT


    Additional Titles:

    Harry Werner Endowed Professor of Equine Medicine

    Chair, Department of Clinical Studies-New Bolton Center


    Dr. Hinrichs obtained her DVM from the University of California, Davis and her PhD from the University of Pennsylvania. Her laboratory has pioneered research in equine assisted reproduction, developing methods to support the clinical application of ICSI that are now utilized worldwide. Most recently, her laboratory published the first efficient protocol for standard equine in vitro fertilization. Dr. Hinrichs’ honors include Theriogenologist of the Year, honorary doctorates from the University of Copenhagen and the University of Ghent, and the Simmet Prize for Assisted Reproduction. She was inducted into the Equine Research Hall of Fame in 2022.

    Angel, D., Canesin, H. S., Brom-de-Luna, J. G., Morado, S., Dalvit, G., Gomez, D., Posada, N., Pascottini, O. B., Urrego, R., Hinrichs, K., Velez, I. C. Embryo development after vitrification of immature and in vitro-matured equine oocytes Cryobiology : , 2020.

    Ripley, A. M., Penedo, M. C. T., Grahn, R. A., Martinez de Andino, E. V., Walbornn, S. R., Serafini, R., Love, C. C., Hinrichs, K. Equine fetal genotyping via aspiration of yolk-sac fluid at 22–28 days of gestation Theriogenology 142: 34-40, 2020.

    Brom-De-Luna, J. G., Salgado, R. M., Canesin, H. S., Diaw, M., Hinrichs, K. Equine blastocyst production under different incubation temperatures and different CO2 concentrations during early cleavage Reproduction, Fertility and Development 31: 1823-1829, 2019.

    Marzano, G., Mastrorocco, A., Zianni, R., Mangiacotti, M., Chiaravalle, A. E., Lacalandra, G. M., Minervini, F., Cardinali, A., Macciocca, M., Vicenti, R., Fabbri, R., Hinrichs, K., Dell’Aquila, M. E., Martino, N. A. Altered morphokinetics in equine embryos from oocytes exposed to DEHP during IVM Molecular Reproduction and Development 86: 1388-1404, 2019.

    Martino, N. A., Marzano, G., Mastrorocco, A., Lacalandra, G. M., Vincenti, L., Hinrichs, K., Dell’Aquila, M. E. Use of time-lapse imaging to evaluate morphokinetics of in vitro equine blastocyst development after oocyte holding for two days at 15°C versus room temperature before intracytoplasmic sperm injection Reproduction, Fertility and Development 31: 1862-1873, 2019.

    Martinez de Andino, E., Brom-de-Luna, J., Canesin, H., Rader, K., Resende, H., Ripley, A., Love, C., Hinrichs, K. Intrafollicular oocyte transfer in the horse: effect of autologous vs. allogeneic transfer and time of administration of ovulatory stimulus before transfer Journal of Assisted Reproduction and Genetics 36: 1237-1250, 2019.

    Lewis, N., Schnauffer, K., Hinrichs, K., Morganti, M., Troup, S., Argo, C. Morphokinetics of early equine embryo development in vitro using time-lapse imaging, and use in selecting blastocysts for transfer Reproduction, Fertility and Development 31: 1851-1861, 2019.

    Kelley, D. E., Hodo, C. L., Aceino, A., Lawhon, S. D., Hinrichs, K., Brinsko, S. P. Abortion due to Bacillus pumilus in a mare Equine Veterinary Education : , 2019.

    Grady, S. T., Watts, A. E., Thompson, J. A., Penedo, M. C. T., Konganti, K., Hinrichs, K. Effect of intra-ovarian injection of mesenchymal stem cells in aged mares Journal of Assisted Reproduction and Genetics 36: 543-556, 2019.

    Grady, S. T., Britton, L., Hinrichs, K., Nixon, A. J., Watts, A. E. Persistence of fluorescent nanoparticle-labelled bone marrow mesenchymal stem cells in vitro and after intra-articular injection Journal of Tissue Engineering and Regenerative Medicine 13: 191-202, 2019.

    Dr. Hinrichs’ research efforts include diagnostic and clinical health areas, such as: 

    • Equine reproductive management
    • Reproductive medicine
    • Embryo transfer
    • Reproductive surgery

    Past research includes:

    • Use of time-lapse imaging to evaluate morphokinetics of in vitro equine blastocyst development
    • Effect of intra-ovarian injection of mesenchymal stem cells in aged mares
    • Equine fetal genotyping via aspiration of yolk-sac fluid at 22-28 days of gestation
    • Intrafollicular oocyte transfer in the horse
    • Conventional vs. Piezo ICSI in the horse: delayed sperm component remodeling and oocyte activation
    • Vitrification of germinal-vesicle stage equine oocytes
    • Culture of somatic cells isolated from frozen-thawed equine semen using fluorescence-assisted cell sorting
    • Accuracy of preimplantation genetic diagnosis in equine in vivo-recovered and in vitro-produced blastocysts
    • Cell lineage allocation in equine blastocysts cultured in varying glucose concentrations
    • Timing factors affecting blastocyst development in equine somatic cell nuclear transfer
    • Regulation of axonemal motility in demembranated equine sperm

    University of Pennsylvania School of Veterinary Medicine (1982 to 1984)
    Resident, Large Animal Reproduction

    Clinical Specialties:

    Equine Reproduction, Reproductive medicine

    Education:

    DVM (Veterinary Medicine-Equine Track) University of California-Davis, 1978 PhD (Biomedical Graduate Group) University of Pennsylvania, 1988

    Board Certification:

    Diplomate, American College of Theriogenologists

    Contact:

    University of Pennsylvania

    School of Veterinary Medicine

    New Bolton Center

    382 West Street Road

    Kennett Square, PA 19348