Instruments & Applications

Leica SP8 Confocal/Multiphoton Microscope

This upright laser scanning confocal microscope has 2-Photon capability, providing the added ability to perform intravital imaging and second harmonic generation (SHG) imaging.

Leica SP5-II Confocal/ Fluorescence Lifetime Imaging Microscope (FLIM)

The fully integrated PicoQuant fluorescence lifetime imaging system on this inverted laser scanning confocal microscope gives users the option of analyzing fluorescent probe distribution based on fluorescence lifetime in addition to fluorescence intensity.

GE DeltaVision OMX Structured Illumination Super-Resolution Microscope

The structured illumination microscopy (SIM) and SIM-TIRF capability that this microscope system provides is ideal for super-resolution imaging of structures around 100 nm in size.

Leica DMI4000 Microscope with Yokagawa CSU-X1 Spinning Disk Confocal Attachment

A full environmental enclosure, programmable motorized stage, and sensitive EM-CCD camera make this spinning disk confocal system ideal for long-term multipoint timelapse microscopy. It is also excellent for large-scale automated tile acquisition and image stitching.

Leica DM6000 Widefield Fluorescence Microscope

This upright widefield microscope is equipped with both color and monochrome cameras, making it suitable for imaging either histology slides or fluorescently labeled samples.

Leica Total Internal Reflection Fluorescence (TIRF) Microscope*

Through evanescent wave illumination that can be adjusted to penetrate as little as 70 nm, events at or near the cell membrane can be imaged with high Z-Axis resolution.

* This microscope is available by special arrangement with the laboratory of Dr. Bruce Freedman.  Please contact Dr. Freedman or the core manager directly to schedule use of the TIRF microscope.

Molecular Devices ImageXpress Micro 4 High Content Imaging Device

This microscope system provides automated imaging and analysis of multiwell culture plates, making it ideal for running either endpoint or live cell assays.

Nikon SMZ1000 Stereo Microscope

The ring light and camera mount on this microscope make it possible to acquire images of small opaque objects, such as a small insect. This stereo microscope is also available to aid in dissection or microsurgery when needed to prepare samples for live imaging on the 2-Photon microscope.

New Brunswick Galaxy 48-S CO2 Incubator

For the convenience of those imaging live cells in culture, this small incubator is available for maintaining cells prior to imaging.