Research Area

    Two men in lab coats look at petri dish

    Stress tested, testing stress: Novel organoid models how the adrenal gland develops (link is external)

    Researchers led by Penn Vet’s Kotaro Sasaki and Michinori Mayama have developed an organoid system that faithfully mimics how the human adrenal gland develops and forms complex tissue structures, providing…

    FAP-CAR T cells deplete tumor associated FAP+ fibroblasts and enhance T-cell infiltration FAP-CAR-tLNPs treated group when compared to control (PBS) group.

    Targeting tumor supporting cells: Advancing CAR T success in pancreatic cancer (link is external)

    Research led by Penn Vet’s Ellen Puré has used lipid nanoparticles to generate CAR T cells directed at a type of tumor support cells—cancer-associated fibroblasts—melting away the protective barrier around…

    Timour Baslan, PhD and Louise Moncla, PhD

    Penn Vet Scientists Earn National Honors for Breakthrough Research in Virology and Cancer Innovation

    Louise Moncla, PhD, receives Ann Palmenberg Junior Investigator Award; Timour Baslan, PhD, named 2026 Damon Runyon–Rachleff Innovation Award recipient

    a person standing in a laboratory with lots of equipment

    Behind the Breakthroughs: Andrew Vaughan

    In this edition, we sit down with Associate Professor of Biomedical Sciences, Andrew “Andy” Vaughan, PhD. Vaughan is a molecular and cellular biologist with a specific interest in lung regeneration.

    Histopathology tissue sections of the normal colon

    Identifying genes that keep cancer from spreading (link is external)

    Using a novel approach, Penn Vet’s Chris Lengner and M. Andrés Blanco and colleagues have identified two genes that suppress colorectal cancer metastasis.

    Three people standing together in front of a projector.

    Penn Vet’s Annual Research Retreat Calls for the Power of Synergy in Challenging Times

    Noting the challenges ahead, but celebrating the many breakthroughs at hand, the University of Pennsylvania School of Veterinary Medicine (Penn Vet) community gathered for their 31st annual Research Retreat held…

    Vet scholars outside getting their photos taken.

    Penn Vet’s Next Gen Biomedical Scientists Present Their Research at the Annual Veterinary Scholars Symposium

    Two dozen budding Penn Vet scientists presented a rich array of ambitious biomedical research projects at the annual Veterinary Scholars Symposium held last month in Spokane, Washington. 

    An image taken through scanning electron microscopy shows healthy mitochondria in brain endothelial cells from 22qDS animals treated with bezafibrate

    Breakthrough Discovery Reveals How Connection Between Mitochondrial Vulnerability and Neurovasculature Function Impacts Neuropsychiatric Disease

    Research from University of Pennsylvania School of Veterinary Medicine and Children’s Hospital of Philadelphia suggests that repurposing a cholesterol drug may benefit 22qDS patients with neuropsychiatric disease

    Eoin Whelan, PhD standing in a lab.

    A new study from Penn Vet on germ cell gene regulatory networks paves way to determine cause of cryopreservation fertility failures

    A study published in Stem Cell Reports, led by Eoin Whelan, PhD, and Ralph Brinster, VMD, PhD, and a team of researchers at the University of Pennsylvania’s School of Veterinary…

    A grid of several different types of cells are shown in this image

    New Study Identifies Promising Inhibitor Combination for Hard-to-Treat Leukemia Subtypes

    Faculty In This Story Assistant Professor of Biomedical Sciences M. Andrés Blanco, PhD, from the University of Pennsylvania’s School of Veterinary Medicine (Penn Vet) and investigators from the Universities of…

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