Study finds buildup of unusual RNA-DNA loops in degenerating photoreceptors, pointing to a shared molecular stress pathway across distinct genetic forms of inherited blindness.
Inherited retinal diseases form a broad and complex group of genetic conditions that cause progressive vision loss and blindness. Dogs, like humans, are susceptible to many such disorders. Because of…
Veterinary ophthalmologists and vision scientists at the University of Pennsylvania’s School of Veterinary Medicine (Penn Vet) have announced the release of DogAEye, an innovative artificial intelligence (AI)–based clinical decision support…
Zoey the cockapoo greeted life with tail-wagging joy. A mass of tawny curls, she loved everyone, and they loved her back.
Efficient delivery of synthetic mRNA to the retina remains one of the key hurdles in developing mRNA-based treatments for vision loss.
Retinal blindness caused by the death of photoreceptors, the light-sensing cells within the retina, affects millions of people worldwide. Novel gene and cell therapies to prevent or rescue vision loss…
Researchers identify metabolic stress as an obstacle to photoreceptor transplantation highlighting a critical window for therapeutic intervention.
A collaborative team of researchers led by vision scientists at the School of Veterinary Medicine have developed novel promoters that drive strong and specific gene expression in rod and cone…
