Penn Vet | Clinical Trials & Research
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Clinical Trials and Research

Clinical Trials & Research in Cancer Care


Penn Vet researchers strive to improve the prevention, diagnosis, and treatment of cancer in animals through novel therapies that may one day offer cancer patients, canine and human alike, a viable alternative or complementary treatment to traditional therapies. Here is a list of current clinical trials in cancer care at Penn Vet.


Current Clinical Trials in Cancer Care

Below is a list of our current clinical trials in cancer care. You may search by animal and by type of cancer.

Please Note

When you choose an animal (Filter by Animal) or when you begin to type something into the 'Filter by Trial Type' field below (e.g., osteosarcoma, etc.), the search results will immediately respond by updating the list of trials. To start over, clear the fields and enter new information.

Clinical evaluation of propranolol and doxorubicin for the treatment of splenic hemangiosarcoma in the dog

In this trial, we will be evaluating Propranolol’s effect on survival time and quality of life when given in combination with the standard chemotherapy treatment.

doxorubicin active splenic HSA splenic hemangiosarcoma spleen propranolol PPL HSA hemangiosarcoma Dr. Pascal Salah Dr. Jennifer Mahoney chemotherapy cancer center cancer active cancer

Comparison of the efficacy & impact on suppressor cells of CHOP vs. LOPP chemotherapy in canine T-cell lymphoma

CHOP vs. LOPP chemotherapy for T-cell Lymphoma

cancer active active lymphoma lymph node chemotherapy cancer

Immunotherapy Clinical Trial for Dogs with Solid Tumors

New clinical trial using a sting agonist for various solid tumor types with a moderate to high risk of metastasis

cancer active active tumor surgery tumor surgery sting agonist squamous cell carcinoma soft tissue sarcoma osteosarcoma mass mammary carcinoma malignant melanoma immunotherapy growth dog cancer dog cancer

Intraoperative Detection and Resection of Tumors in Canines Using an Integrated Spectroscopy and Imaging System

A clinical trial to determine if near-infrared imaging can improve the surgeon’s ability to see cancer and cancer margins during surgery to remove primary lung tumors in dogs.

cancer active tumor surgery primary lung tumor Oncology metastasis mass margins lung tumor lung mass lung infrared Imaging Dr. David Holt diagnostic imaging comprehensive cancer care canine tumor canine lung tumor canine cancer cancer center cancer advanced imaging active

Pilot Study of xenograft chimeric antigen receptor T cell therapy for drug resistant or refractory CD20+ B cell Lymphoma

T cell therapy for drug resistant B cell Lymphoma

Mason Active lymphoma dogs canine cancer active cancer B-cell lymphoma active

Re-directed Autologous T cell Therapy for B cell lymphoma or B Cell Leukemia

Immune cells (known as T cells) are taken from the peripheral blood, stimulated, expanded and genetically modified in the laboratory to express a surface receptor that recognizes B cells

Mason Active immunotherapy comprehensive cancer care canine lymphoma canine cancer cancer center cancer active cancer b-cell malignancies B-cell lymphoma active

Soft Tissue Sarcoma & Mammary Carcinoma - Photoacoustic System for Identifying Tumor Edges (PSITE)

inactive tumor removal tumor soft tissue sarcoma mammary carcinoma cancer center cancer active cancer

Use of Near-infrared Imaging in Surgical Accuracy for Feline Soft-Tissue Sarcomas

Penn Vet is conducting a study to determine if near-infrared imaging can improve the surgeon’s ability to see cancer and cancer margins during surgery to remove feline soft tissue sarcomas.

inactive ryan surgery infrared imaging feline soft tissue sarcoma david holt cancer active

Penn Vet's VCIC

Penn Vet, Veterinary Clinical Investigations CenterPenn Vet’s Veterinary Clinical Investigations Center (VCIC) works with regional veterinary clinics to offer patients access to cutting-edge clinical trials. These trials can offer owners potential diagnostic and treatment options that are not available anywhere else locally or even nationally for their pet.

The VCIC provides nursing staff dedicated to helping owners and their pets navigate the course of enrolling in a clinical trial, offering them state-of-the-art care, while informing science for the benefit of future generations of pets and people alike.

Learn more about Penn Vet's VCIC...


About Cancer Research at Penn Vet

Ms12 in tumorFaculty and clinicians at Penn Vet are actively engaged in groundbreaking research in cancer care. From developing an immunotherapeutic treatment for canine osteosarcoma to genetic rewiring, we are leaders in innovative approaches to treating cancer. Some of our faculty's results are now being used in human clinical trials.  Learn about the range of basic and translational research taking place in cancer at Penn Vet.