New Bolton Center Kennett Square, PA
Emergencies & Appointments:
Ryan Hospital Philadelphia, PA


Diplomate, American College of Veterinary Ophthalmologists

Assistant Professor, Ophthalmology, University of Pennsylvania School of Veterinary Medicine

Clinical Specialties: Inherited diseases of the eye in animals
Research Areas: Molecular basis of inherited retinal degeneration in dogs

Contact Information:

Keiko Miyadera, Laura Conatser, Telmo A Llanga, Kendall Carlin, Patricia O'Donnell, Jessica Bagel, Liujiang Song, Joanne Kurtzberg, R Jude Samulski, Brian Gilger, Matthew L Hirsch Intrastromal Gene Therapy Prevents and Reverses Advanced Corneal Clouding in a Canine Model of Mucopolysaccharidosis I Molecular Therapy 28: 1455-1463, 2020.

Das Rueben G, Becker Doreen, Jagannathan Vidhya, Goldstein Orly, Santana Evelyn, Carlin Kendall, Sudharsan Raghavi, Leeb Tosso, Nishizawa Yuji, Kondo Mineo, Aguirre Gustavo D, Miyadera Keiko Genome-wide association study and whole-genome sequencing identify a deletion in LRIT3 associated with canine congenital stationary night blindness. Scientific reports 9: 14166, 2019.

Das Rueben G, Marinho Felipe Pompeo, Iwabe Simone, Santana Evelyn, McDaid Kendra Sierra, Aguirre Gustavo D, Miyadera Keiko Variabilities in retinal function and structure in a canine model of cone-rod dystrophy associated with RPGRIP1 support multigenic etiology. Scientific reports 7: 12823, 2017.

Forman Oliver P, Hitti Rebekkah J, Boursnell Mike, Miyadera Keiko, Sargan David, Mellersh Cathryn Canine genome assembly correction facilitates identification of a MAP9 deletion as a potential age of onset modifier for RPGRIP1-associated canine retinal degeneration. Mammalian genome : official journal of the International Mammalian Genome Society 27: 237-45, 2016.

Tanaka N, Dutrow EV, Miyadera K, Delemotte L, MacDermaid CM, Reinstein SL, Crumley WR, Dixon CJ, Casal ML, Klein ML, Aguirre GD, Tanaka JC, Guziewicz KE Canine CNGA3 Gene Mutations Provide Novel Insights into Human Achromatopsia-Associated Channelopathies and Treatment. PloS one 10: e0138943, 2015.

Kondo M, Das G, Imai R, Santana E, Nakashita T, Imawaka M, Ueda K, Ohtsuka H, Sakai K, Aihara T, Kato K, Sugimoto M, Ueno S, Nishizawa Y, Aguirre GD, Miyadera K A Naturally Occurring Canine Model of Autosomal Recessive Congenital Stationary Night Blindness. PloS one 10: e0137072, 2015.

Miyadera K Inherited retinal diseases in dogs: advances in gene/mutation discovery. Dobutsu iden ikushu kenkyu = Journal of animal genetics 42: 79-89, 2014.

Miyadera K, Kato K, Boursnell M, Mellersh CS, Sargan DR Genome-wide association study in RPGRIP1(-/-) dogs identifies a modifier locus that determines the onset of retinal degeneration. Mammalian genome : official journal of the International Mammalian Genome Society 23: 212-23, 2012.

Miyadera K, Acland GM, Aguirre GD Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies. Mammalian genome : official journal of the International Mammalian Genome Society 23: 40-61, 2012.

Miyadera K, Brierley I, Aguirre-Hernández J, Mellersh CS, Sargan DR Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy. PloS one 7: e51598, 2012.

DVM (Veterinary Medicine) University of Tokyo, Japan, 2005

PhD (Molecular Biology) University of Cambridge, United Kingdom, 2011

Diplomate, American College of Veterinary Ophthalmologists

University of Pennsylvania (2012 to 2015)
Residency in Ophthalmology