Current Clinical Trials at Penn Vet

Learn about our current clinical trials by browsing through this list. You can sort by animal, or search by disease type.
Evaluating a Therapeutic Mattress for Dogs with Osteoarthritis
This clinical trial is assessing a therapeutic mattress for dogs who are suffering from osteoarthritis Google arthritis active osteoarthritis limping arthritis active
Clinical Trial Using Immunotherapy For Dogs With Transitional Cell Carcinoma
Transitional cell carcinoma (TCC) is the most common type of bladder cancer in dogs. Mason Active transitional cell carcinoma TCC Mason TCC carcinoma Canine carcinoma canine bladder cancer bladder cancer in dogs bladder cancer active
Clinical Trial for dogs who had a Cranial Cruciate Ligament (CCL) Rupture & TPLO Surgery
Assessing novel therapeutic that will be evaluated for its effect on the development and progression of osteoarthritis in dogs following CCL rupture and TPLO surgery Google arthritis active TPLO knee surgery CCL rupture CCL arthritis active
The Use of an Intraluminal stent in Canine Laryngeal Paralysis
This study evaluates whether this stent is an effective treatment for laryngeal paralysis in dogs. difficulty eating difficulty breathing respiratory distress raspy bark canine laryngeal paralysis active
Coagulation in Septic Peritonitis in Dogs
We are testing a heparin derivative that is anti-inflammatory without being anticoagulant. abdomen septic belly septic abdomen septic peritonitis active
A Study Evaluating an Injectable Treatment for Dogs with Elbow Arthritis
A Pilot Study to Evaluate an Intra-articular Injection for Dogs with Elbow Arthritis joint x rays orthopedic elbow dysplasia canine clinical trial limping elbow pain pain meds Rimadyl active painful pain
Clinical Trial Using Immunotherapy For Dogs With Osteosarcoma
Dogs enrolled in this upcoming clinical trial will receive a HER2-targeting bacterial vaccine after amputation and chemotherapy. Mason Active osteosarcoma Mason Cancer Studies immunotherapy canine cancer cancer active
Safety And Effectiveness Of Antibody Therapy For Dogs With Splenic Hemangiosarcoma
This trial evaluates the safety and effectiveness of an antibody therapy designed to inhibit VEGF and delay or prevent spread of hemangioscarcoma after surgery Mason hemangiosarcoma Mason Cancer Studies Mason Active immunotherapy hemangiosarcoma canine hemangiosarcoma canine cancer cancer active
Clinical Trial for Dogs with Osteosarcoma
Assessing standard of care chemotherapy +/- a new oral medication for dogs with bone cancer chemo chemotherapy OSA cancer treatment active amputation leg amputation study research leg tumor sarcoma osteo bone bone tumor dog cancer cancer canine
Novel Therapeutic for Dogs with Cataracts
STUDY ON HOLD-A new plant-derived topical treatment to improve vision in dogs with cataract disease ophthalmologist vision blind eye active
Assessing a Cell-Based Therapy in Dogs with Arthritis
A new study for dogs with arthritis of the knee. Google arthritis active stem cell radio ad painful pain meds NSAIDs new study limping KYW joint pain clinical trial bad knees arthritis active
Use of Near-infrared Imaging in Surgical Accuracy for Feline Soft-Tissue Sarcomas
Penn Vet is conducting a study to determine if near-infrared imaging can improve the surgeon’s ability to see cancer and cancer margins during surgery to remove feline soft tissue sarcomas. active ryan surgery david holt infrared imaging feline soft tissue sarcoma
Trial of ALVAC® IL-2 Treatment in Cats with Feline Fibrosarcoma
Clinical trial evaluating surgery in combination with immunotherapy for cats with fibrosarcoma surgery tumor FSA vaccine cancer active
Re-directed Autologous T cell Therapy for drug resistant or refractory CD20+ B cell lymphoma
Immune cells (known as T cells) are taken from the peripheral blood, stimulated, expanded and genetically modified in the laboratory to express a surface receptor that recognizes B cells Mason Active Mason Cancer Studies mason immunotherapy canine lymphoma canine cancer cancer b-cell malignancies B-cell lymphoma active
RNA-transfected CD40-B Cell Vaccines for Dogs With Newly Diagnosed Lymphoma
Determine whether a cell based vaccine can prevent the return of lymphoma after standard chemotherapy treatment. Mason Active Mason Cancer Studies lymphoma immunotherapy canine lymphoma canine cancer cancer active
Long term, clinical outcome of patellofemoral osteoarthritis in dogs with naturally occurring unilateral cranial cruciate ligament rupture
A clinical trial evaluating the outcome of dogs with knee joint arthritis due to the rupture of the Cranial Cruciate Ligament in one knee joint, then stabilized with the Tibial Plateau Leveling Osteotomy (TPLO) procedure VCIC TPLO tibial plateau leveling osteotomy osteoarthritis orthopedic ligament rupture knee joint cruciate tear cranial cruciate ligament CCL Agnello active
New Study for Dogs with Chronic Gastrointestinal Upset
We are currently enrolling dogs with signs of Canine Chronic Enteropathy, sometimes caused by Inflammatory Bowel Disease, in a clinical trial looking at the naturally occuring bacteria of the GI tract throughout treatment. weight loss vomiting VCIC PLE Inflammatory bowel disease IBD food sensitivity diarrhea chronic active
Effect of duration of red blood cell storage on transfusion-associated inflammation in dogs with IMHA and IMT
We propose to evaluate markers of inflammation, hemolysis, and endothelial activation in a randomized clinical trial in which dogs with primary immune-mediated hemolytic anemia and immune-mediated thrombocytopenia would receive fresh or old RBCs. canine anemia transfusion thrombocytopenia red blood cell IMT IMHA hemodyalisis blood type anemia active
Supplement for Dogs with Splenic Hemangiosarcoma
In this trial, we will be comparing I’m-Yunity’s® effect on survival time and quality of life to the standard chemotherapy treatment. VCIC turkey tail mushroom splenic HSA spleen mushroom I’m-Yunity HSA hemangiosarcoma cancer alternative medicine active
Vitamin B12 in Cats with Lymphoma
Measuring Vitamin B12 and MMA levels in Cats Diagnosed with Lymphoma. VCIC cancer B12 active
Weight Loss in Cats with Cancer
Study evaluating body weight, muscle mass and inflammatory markers in cats with cancer. cancer Cancer Cachexia active