Current Clinical Trials at Penn Vet
Learn about our current clinical trials by browsing through this list. You can sort by animal, or search by disease type.
Evaluation of the Safety and Effectiveness of the Immunicom Apheresis Immunoabsoption Affinity Column in Combination with the Terumo BCT Spectra Optia Apheresis System ® for the treatment of Malignant Melanoma in the Dog
A clinical trial assessing the effectiveness and safety of the clinical outcome of dogs with measurable malignant melanoma using the treatment of Apheresis.
Re-directed Autologous T cell Therapy for drug resistant or refractory CD20+ B cell lymphoma
Immune cells (known as T cells) are taken from the peripheral blood, stimulated, expanded and genetically modified in the laboratory to express a surface receptor that recognizes B cells
RNA-transfected CD40-B Cell Vaccines for Dogs With Newly Diagnosed Lymphoma
Determine whether a cell based vaccine can prevent the return of lymphoma after standard chemotherapy treatment.
DOGhOUSE Quality of Life Study
Develop and validate a questionnaire for the impact of dog ownership on human quality of life.
Validation of the Reptile Brief Pain Inventory
A clinical trial designed to evaluate health and behavioral changes related to orthopedic disease in pet lizards
The impact of CT Scans on Surgical Planning for Ferrets with Insulinoma
PENN VET is recruiting ferrets with INSULINOMA to participate in a study evaluating CT scans for surgical planning.
Canine Cardiovascular-Renal Disorder Study
This study investigates dogs with possible cardiac dysfunction resulting from chronic kidney disease (called Type 4 cardiorenal (or Renocardiac) syndrome.
Novel therapeutic for chronic knee arthritis pain in dogs
Assessing the efficacy and optimal dose of a single intra-articular injection of CNTX-4975 for the control of pain due to chronic knee arthritis in dogs.
Long term, clinical outcome of patellofemoral osteoarthritis in dogs with naturally occurring unilateral cranial cruciate ligament rupture
A clinical trial evaluating the outcome of dogs with knee joint arthritis due to the rupture of the Cranial Cruciate Ligament in one knee joint, then stabilized with the Tibial Plateau Leveling Osteotomy (TPLO) procedure
Evaluating the Role of the Microbiome in the Resolution of Canine Chronic Enteropathy
We are currently enrolling dogs with signs of Canine Chronic Enteropathy, sometimes caused by Inflammatory Bowel Disease, in a clinical trial looking at the naturally occuring bacteria of the GI tract throughout treatment.
Evaluation of combined palliative radiation and ADXS31-164 in dogs with appendicular osteosarcoma (OSA)
Study evaluates whether vaccination with a new tumor-targeting cancer vaccine combined with radiation therapy can decrease bone cancer pain and prolong overall survival in dogs with OSA.
Prospective clinical trial to evaluate two diets in the nutritional management of dogs with acute diarrhea
Evaluating the clinical responses of dogs with acute diarrhea that are temporarily fed with on of two commercially available canned diets formulated to help in the management of acute diarrhea associated with mild gastrointestinal disease.
Evaluating the Effects of Acupuncture on Chemotherapy-Induced Side Effects in Dogs With Lymphoma
A clinical trial looking at acupuncture used together with traditional chemotherapy
A Pilot Trial Evaluating the Effects of Plant-Derived Supplements in Geriatric Dogs
This trial evaluates a plant-based supplement intended to improve activity level, functional mobility, and overall quality of life.
Evaluation of Silymarin in Canine Protein Losing Nephropathy
This pilot research study will evaluate the effect of giving dogs with PLN silymarin in combination with established standard medications.
Clinical Assessment of Stem Cell Therapy for Dogs with Fragmented Medial Coronoid Processes
PennVet is enrolling young dogs with elbow dysplasia for a study to assess and optimize the benefits of stem cell therapy following arthroscopic surgery for fragmented medial coronoid processes.
Effect of duration of red blood cell storage on transfusion-associated inflammation in dogs with IMHA and IMT
We propose to evaluate markers of inflammation, hemolysis, and endothelial activation in a randomized clinical trial in which dogs with primary immune-mediated hemolytic anemia and immune-mediated thrombocytopenia would receive fresh or old RBCs.
Further Evaluation of the Benefits of a Traditional Chinese Medicine Supplement for Dogs with Splenic Hemangiosarcoma
In this trial, we will be comparing I’m-Yunity’s® effect on survival time and quality of life to the standard chemotherapy treatment.
Cats with Diabetic Ketoacidosis
Treatment of Feline Diabetic Ketoacidosis with Lispro Insulin.
Vitamin B12 in Cats with Lymphoma
Measuring Vitamin B12 and MMA levels in Cats Diagnosed with Lymphoma.
Weight Loss in Cats with Cancer
Study evaluating body weight, muscle mass and inflammatory markers in cats with cancer.
Study of Protein-losing Enteropathy/Nephropathy, Addison’s disease and Renal Disease in Soft-coated Wheaten Terriers
Study recruiting both Wheaten Terriers and other breeds of dogs afflicted with inflammatory bowel disease, protein losing enteropathy, protein losing nephropathy, Addison’s disease or juvenile renal disease/dysplasia.
Study of Lyme Nephritis and Protein-losing Enteropathy/Nephropathy in Dogs
Data collecting study for dogs with Lyme nephritis or protein-losing enteropathy.
Imaging Soft Tissue Sarcomas During Surgery
Clinical study to help improve detection of surgical margins during tumor removal.
Tooth Resorption in Dogs
Study characterizing tooth resorption and the factors that contribute to it.
Tooth Extractions in Dogs
Evaluation of osteoconductive or osteoinductive materials in bone formation of tooth extraction sites.
Comparison of Three New Medications for Dogs with Lymphoma
Evaluation of three new medications for dogs with lymphoma.
New Insulin Combination for Dogs with Well-Regulated Diabetes
Study investigating Lispro insulin to be used in combination with traditional NPH insulin.
Imaging Primary Lung Tumors During Surgery
Clinical study to help improve the detection of surgical margins in dogs with primary lung tumors.