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Current Clinical Trials at Penn Vet


Learn about our current clinical trials by browsing through this list. You can sort by animal, or search by disease type.
Imaging Primary Lung Tumors During Surgery
Clinical study to help improve the detection of surgical margins in dogs with primary lung tumors. lymph node cancer active
New Insulin Combination for Dogs with Well-Regulated Diabetes
Study investigating Lispro insulin to be used in combination with traditional NPH insulin. active
Comparison of Three New Medications for Dogs with Lymphoma
Evaluation of three new medications for dogs with lymphoma. chemotherapy cancer active
Tooth Extractions in Dogs
Evaluation of osteoconductive or osteoinductive materials in bone formation of tooth extraction sites. tooth extraction active
Tooth Resorption in Dogs
Study characterizing tooth resorption and the factors that contribute to it. active
Imaging Soft Tissue Sarcomas During Surgery
Clinical study to help improve detection of surgical margins during tumor removal. tumor cancer active
Study of Lyme Nephritis and Protein-losing Enteropathy/Nephropathy in Dogs
Data collecting study for dogs with Lyme nephritis or protein-losing enteropathy. tick-born lump renal disease active
Study of Protein-losing Enteropathy/Nephropathy, Addison’s disease and Renal Disease in Soft-coated Wheaten Terriers
Study recruiting both Wheaten Terriers and other breeds of dogs afflicted with inflammatory bowel disease, protein losing enteropathy, protein losing nephropathy, Addison’s disease or juvenile renal disease/dysplasia. Wheaten Terrier active
Weight Loss in Cats with Cancer
Study evaluating body weight, muscle mass and inflammatory markers in cats with cancer. cancer Cancer Cachexia active
Vitamin B12 in Cats with Lymphoma
Measuring Vitamin B12 and MMA levels in Cats Diagnosed with Lymphoma. cancer active B12
Cats with Diabetic Ketoacidosis
Treatment of Feline Diabetic Ketoacidosis with Lispro Insulin. insulin diabetes active
Further Evaluation of the Benefits of a Traditional Chinese Medicine Supplement for Dogs with Splenic Hemangiosarcoma
In this trial, we will be comparing I’m-Yunity’s® effect on survival time and quality of life to the standard chemotherapy treatment. turkey tail mushroom splenic HSA spleen mushroom I’m-Yunity HSA hemangiosarcoma cancer alternative medicine active
Effect of duration of red blood cell storage on transfusion-associated inflammation in dogs with IMHA and IMT
We propose to evaluate markers of inflammation, hemolysis, and endothelial activation in a randomized clinical trial in which dogs with primary immune-mediated hemolytic anemia and immune-mediated thrombocytopenia would receive fresh or old RBCs. active anemia blood type hemodyalisis IMHA IMT red blood cell thrombocytopenia transfusion
Clinical Assessment of Stem Cell Therapy for Dogs with Fragmented Medial Coronoid Processes
PennVet is enrolling young dogs with elbow dysplasia for a study to assess and optimize the benefits of stem cell therapy following arthroscopic surgery for fragmented medial coronoid processes. active arthritis
Desmopressin Therapy and Chemotherapy for Dogs with Hemangiosarcoma
Evaluate the safety, efficacy and tolerability of Desmopressin in conjunction with chemotherapy in canine hemangiosarcoma. spleenectomy spleen cancer active
Evaluation of Silymarin in Canine Protein Losing Nephropathy
This pilot research study will evaluate the effect of giving dogs with PLN silymarin in combination with established standard medications. proteinuria kidney nephropathy active
A Pilot Trial Evaluating the Effects of Plant-Derived Supplements in Geriatric Dogs
This trial evaluates a plant-based supplement intended to improve activity level, functional mobility, and overall quality of life. active alternative medicine complementary medicine geriatric older dog
Evaluating the Effects of Acupuncture on Chemotherapy-Induced Side Effects in Dogs With Lymphoma
A clinical trial looking at acupuncture used together with traditional chemotherapy alternative medicine complementary medicine active cancer
A New Oral Chemotherapy for Dogs with Osteosarcoma Following Limb Amputation
Assessing the efficacy of Palladia® in decreasing the spread of osteosarcoma and prolonging life active bone cancer osteosarcoma
Prospective clinical trial to evaluate two diets in the nutritional management of dogs with acute diarrhea
Evaluating the clinical responses of dogs with acute diarrhea that are temporarily fed with on of two commercially available canned diets formulated to help in the management of acute diarrhea associated with mild gastrointestinal disease. poop bowel movement soft stools active diarrhea gastrointestinal
Mason Lab: Evaluation of combined palliative radiation and ADXS31-164 in dogs with appendicular osteosarcoma (OSA)
This study is now closed. Study evaluates whether vaccination with a new tumor-targeting cancer vaccine combined with radiation therapy can decrease bone cancer pain and prolong overall survival in dogs with OSA. osteosarcoma immunotherapy cancer vaccine active
Evaluating the Role of the Microbiome in the Resolution of Canine Chronic Enteropathy
We are currently enrolling dogs with signs of Canine Chronic Enteropathy, sometimes caused by Inflammatory Bowel Disease, in a clinical trial looking at the naturally occuring bacteria of the GI tract throughout treatment. weight loss vomitting PLE Inflammatory bowel disease IBD food sensitivity diarrhea chronic active
Long term, clinical outcome of patellofemoral osteoarthritis in dogs with naturally occurring unilateral cranial cruciate ligament rupture
A clinical trial evaluating the outcome of dogs with knee joint arthritis due to the rupture of the Cranial Cruciate Ligament in one knee joint, then stabilized with the Tibial Plateau Leveling Osteotomy (TPLO) procedure TPLO tibial plateau leveling osteotomy osteoarthritis orthopedic ligament rupture knee joint cruciate tear cranial cruciate ligament CCL Agnello active