Care for horses & livestock/farm animals
Care for cats, dogs & other companion animals
Related Terms: CD18 Deficiency, FLAD, ITGB2
Sample Types: Cheek brushes/swabs or Fresh EDTA blood
This type of test request requires a pre approval. Please email PennGen@vet.upenn.edu to get pre approval before taking any samples. If you don't get a pre approval your request will be cancelled.
2 months of age
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We do not provide kits. Please collect the sample following the sample collection and shipping instructions before ordering a test.
The disease is characterized by recurrent infections, periodontitis, and the lifelong need for antibiotic treatment.
Prognosis appears to be better than in other species. With continued antibiotic therapy, expect a relatively long lifespan.
Dependent on the degree and site of infection.
ITGB2 and XM_011285804.3:c.46_58+11del
Bauer TR Jr, Pratt SM, Palena CM, Raj K, Giger U. Feline leukocyte adhesion (CD18) deficiency caused by a deletion in the integrin ß2 (ITGB2) gene. Vet Clin Pathol. 2017 Sep;46(3):391-400. doi: 10.1111/vcp.12526. Epub 2017 Jul 27. PMID: 28750142; PMCID: PMC5610637.