Penn Vet | Clinical Trial Detail
New Bolton Center Kennett Square, PA
Emergencies & Appointments:
Ryan Hospital Philadelphia, PA

Embolization or chemoembolization in dogs with hepatocellular carcinoma and utility of contrast-enhanced ultrasound versus CT angiogram in post-embolization assessment.

This trial will compare outcomes in dogs treated with embolization vs. chemoembolization and will also evaluate the accuracy of contrast enhanced ultrasound verses CT angiogram for post-embolization assessment.

active liver tumors liver cancer hepatocellular carcinoma Embolization dogs with liver tumors dogs with liver cancer CT angiogram Contrast-enhanced ultrasound Chemoembolization

Evaluation of VetResQ® Hemoperfusion Cartridge for Treatment of Non-Steroidal Anti-Inflammatory Drug (NSAID) Toxicity in Dogs and Cats

The aim of this study is to document how much NSAID is removed from the blood during treatment with VetResQ® hemoperfusion cartridge.

Reineke toxicity poisoning NSAID Extracorporeal Therapies active

Intraoperative assessment of marginal tissue after BCS resection using in-vivo topical application of a cathepsin-targeted molecular probe.

Evaluating the efficacy of a new near-infrared imaging agent when applied topically to tumor during surgery in dogs with mammary gland tumors

mastectomy near-infrared imaging NIRI breast cancer mammary adenocarcinoma mgt mammary gland tumor mammary tumor mammary carcinoma active massie holt clinical trial Holt

Amantadine in conjunction with carprofen for improvement of lameness and pain secondary to osteoarthritis in dogs

The purpose of this study is to determine the efficacy of amantadine in combination with carprofen, a non-steroidal anti-inflammatory drug (NSAID) already approved for use in dogs, to manage refractory pain associated with osteoarthritis in dogs

active osteoarthritis Amantadine Agnello

Intraoperative detection of oral squamous cell carcinoma margins in dogs using cathepsin-activated near-infrared (NIR) imaging

A clinical trial evaluating a new near-infrared (NIR) imaging agent to detect cancerous tissue in dogs with oral squamous cell carcinoma (SCC) during surgical excision.

active surgery squamous cell carcinoma skin cancer SCC oral tumor NIRI near-infrared imaging mouth Holt Griffin epithelium epidermis Castejon cancer

Use of a newly available glargine (Semglee®) for treatment of diabetes mellitus in cats

This clinical trial will help determine if Semglee is as effective as glargine in regulating diabetes in cats.

Semglee insulin FreeStyle Libre glucose diabetic cat Nelson Mampe Rebecka hess feline diabetes clinical trial active

Sentinel lymph node mapping for canine thyroid carcinoma

A clinical trial to develop SLN mapping techniques in dogs with thyroid tumors (to aid in early detection and removal of cancerous lymph nodes) and to evaluate their utility and agreement.

thyroid carcinoma cancer clinical trial active

Untargeted plasma metabolomics and biomarker, DNA, and microbiome assessments in cats with and without chronic kidney disease

This study is looking to identify unique biomarkers in cats with chronic kidney disease and improve outcomes.

urinary clinical trial chronic kidney disease active

Evaluation of FLASH Proton RT in Naturally Occurring Canine Head and Neck Cancer

The purpose of this study is to evaluate the safety and feasibility of a novel form of radiation therapy (RT) called FLASH proton radiation therapy for head and neck cancers in dogs.

cancer Oncology radiation active clinical trial

The role of chronic inflammation on behavior and cognition of aging cats

Cognition in older cats

active cognitive function healthy aging inflammation cats healthy Siracusa behavior cognition aging aging pets

CLASSIC Plus: Cancer Lifetime Assessment Screening Study in Canines (CLASSiC)

Assessing the use of ONCOK9, a multi-cancer early detection test

cancer monitoring healthy aging healthy cancer screening cancer active Brian Flesner

The Utility of OncoK9 Liquid Biopsy for the Detection of Canine Insulinoma

This trial will be determine if Oncok9 Liquid Biopsy kit can detect insulinoma cells in the blood of dogs.

active pancreatic cancer Insulinoma clinical trial dog

Cathepsin-activated near-infrared (NIR) imaging for intraoperative detection of insulinomas

A clinical trial evaluating a new near-infrared imaging agent to detect cancerous tissue in dogs with Insulinoma during surgical excision.

pancreatic Insulinoma clinical trial cancer active

Sentinel lymph node mapping for canine apocrine gland anal sac adenocarcinoma

The aims of this study are to develop SLN mapping techniques in dogs with anal sac tumors (to aid in early detection and removal of cancerous lymph nodes) and to evaluate their utility and agreement.

active sacculectomy lymph node AGASACA carcinoma anal gland cancer anal sac tumor dog

Evaluation of Bendamustine as a Novel Chemotherapy Agent for Relapsed Canine Lymphoma

The purpose of this study is to evaluate different doses of bendamustine in dogs with lymphoma to evaluate its safety and effectiveness.

active chemotherapy lymphoma dogs

Fosmidomycin Otic Trial for dogs

Dermatology is currently enrolling in a clinical trial evaluating a novel, topical antimicrobial for dogs with bilateral otitis.

ear infection in dogs canine otitis active

Community Population Prevalence of SARS-CoV-2 in Cats and Dogs

A study to determine the prevalence of SARS-CoV-2 (the virus that causes COVID-19) in the local pet population

Covid in pets COVID-19 coronavirus active

Intraoperative Detection and Resection of Tumors in Canines Using an Integrated Spectroscopy and Imaging System

A clinical trial to determine if near-infrared imaging can improve the surgeon’s ability to see cancer and cancer margins during surgery to remove primary lung tumors in dogs.

cancer active tumor surgery primary lung tumor Oncology metastasis mass margins lung tumor lung mass lung infrared Imaging Dr. David Holt diagnostic imaging comprehensive cancer care canine tumor canine lung tumor canine cancer cancer center cancer advanced imaging active

Comparison of the efficacy & impact on suppressor cells of CHOP vs. LOPP chemotherapy in canine T-cell lymphoma

CHOP vs. LOPP chemotherapy for T-cell Lymphoma

cancer active active lymphoma lymph node chemotherapy cancer

Coagulation in Septic Peritonitis in Dogs

We are testing a heparin derivative that is anti-inflammatory without being anticoagulant.

abdomen septic belly septic abdomen septic peritonitis active

Long term study assessing outcome of knee arthritis in dogs with cruciate ligament (CCL) rupture

A clinical trial evaluating the outcome of dogs with patellofemoral osteoarthritis due to the rupture of the Cranial Cruciate Ligament in one stifle, then stabilized with the Tibial Plateau Leveling Osteotomy (TPLO) procedure

Dr. Kimberly Agnello VCIC TPLO tibial plateau leveling osteotomy stifle osteoarthritis orthopedic limping ligament rupture knee joint cruciate tear cruciate cranial cruciate ligament CCL arthritis Agnello active ACL